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                  Question 3 
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                  (a)(i) What is an endocrine gland? [2 marks]  
(ii) 
                      State  three functions of adrenalin. [3 marks] 
                      (b) State three effects of each of the following conditions in  humans:  
(i) over-secretion of thyroxin;  
(ii) under-secretion of thyroxin.[6 marks]  
(c) (i) Write HIV in full. [ 1 mark]  
(ii) Distinguish between HIV and AIDS. [2 mark]  
                    (d)State two methods each by which the  vectors of the following diseases can be controlled:  
(i)  onchocerciasis;  
(ii) schistosomiasis;  
(iii) guinea worm. [ 6 marks]                     
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                  This question was attempted by few candidates and candidates performance  was fair. In part (a)(i) 
candidates could not define  endocrine gland correctly in (a) (ii) candidates lost  marks because they 
cannot state functions of adrenalin. In  part (b) however, candidates lost marks because they mixed 
up effect of over-secretion of thyroxin with effect of under-secretion  of thyroxin. In part ( c) (i) 
candidates lost marks  due to their inability to write HIV in full, some candidates wrote  Human 
immino deficiency while some wrote immune only, in  (c) (ii) candidates could not distinguish 
between HIV and AIDS. In part  (d) candidates could not state the method of controlling the  vectors 
of onchocerciasis, schistosomiasis and guinea worm, few  candidates that stated the methods mixed 
up onchocerciasis for guinea worm and schistosomiasis for  onchocerciasis.  
The expected answers were as follows
                     
                    (a)(i) Endocrine gland  
Is a gland whose secretion does not pass through any duct/ductless  before reaching its target  
organ/ductless gland which secretes directly into the  blood.  
(ii) Functions of  adrenal in  
increasing the rate of conversion  of glucose to glycogen  
controls response for fight or flight/prepares  the body for action  
increases the rate of heart beat  
it increases muscle tones  
it increases rate of breathing action  
 increases blood sugar level. (b) Effects of the following conditions in humans  
(i) Over-secretion of thyroxin  
thyroid gland becomes large/goiter  develops  
increases rate of heart beat  
large appetite is developed  
there is loss in body weight  
sleeplessness/nervousness/anxiety  
rate of metabolism is increased  
increase in blood pressure  
(ii) Under-secretion of  thyroxin  
rate of metabolism decreases  
rate of heart beat decreases  
body temperature is lowered  
children become stunted in growth  
children have poor mental development  
adults develop thick skin.  
(c) (i) HIV  in full  
Human Immuno Deficiency Virus  
(ii) Distinguishing between HIV and AIDS  
HIV is a virus and AIDS is a disease caused by the  virus  
(d)Method by which the vectors of the following diseases can  be controlled  
(i) Ochocerciasis 
clear bush around banks of river/allow  free flow of stream.  
treat breeding places with insecticides  
(ii) Schistosomiasis 
Introduce fish to eat intermediate  host (water snail)  
eliminate the water snail with mollusc  ide  
clear vegetation around pond/destroy breeding  grounds  
prevent infected person from urinating or defecating  into waters  
avoid bathing in infected water.  
(iii)Guinea  worm  
boil drinking water/provide  good source of water.  
filter water before drinking  
avoid wading or bathing in water/streams.  
rivers/lakes/ponds wear rain boot.  
destroy intermediate host.  
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